FEATURES

Compound Interest
By Jennifer Durgin

What if the way to win the war on cancer is not to cure tumors but to keep them from forming in the first place? Dartmouth's Michael Sporn, known as the "father of chemoprevention," has devoted his career to that question. Now he and his collaborators have two compounds in clinical trials—compounds that may stop tumors before they start.

Cold Comfort
By Laura Stephenson Carter

If an influenza pandemic strikes again, it could be cold comfort to know that lessons learned from the 1918 flu epidemic may offer more help than modern medicine. Here are some insights gleaned from the Dartmouth archives and from a Dartmouth graduate who studies pandemics.

Turning Thirty

Dartmouth Medicine was spawned in 1976, when the dictum "Don't trust anyone over thirty" was still in vogue. In the three decades since then—through one name change, several redesigns, many production improvements, and, most significantly, countless changes in its subject matter—the magazine has endeavored to earn the trust of readers, to engage you in Dartmouth medicine.

COVER

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February 16, 1998—as recorded in this lab notebook (check out the impeccable handwriting!)—was an auspicious day for a team of Dartmouth chemoprevention researchers. See "Compound Interest" for the associated feature. The cover photo is by Jon Gilbert Fox.

DEPARTMENTS

Editor's Note

Discoveries

 SPORT utility
 Modeling the heart
 Skin cancer insight
 . . .and more

Vital Signs

 Dr. Koop turns 90
 A brain trust
 Pharmacogenomic pioneers
 Rebirth in Kosovo
 . . .and more

Letters

Point of View

By David L. Katz, M.D., M.P.H.

Student Notebook

By Debraj Mukherjee

Transforming Medicine Campaign

Faculty Focus

David Goodman, M.D.

Alumni Album

Robert Michler, M.D., '81

Grand Rounds

By Peter K. Spiegel, M.D.

Art of Medicine

Prachie Narain