Moore and More
Despite his affinity for high-tech gadgetry, Jason Moore spends his time thinking about a very old idea. His genetics research focuses on the idea of epistasis—the interaction of genes. And he worries that the rush to develop increasingly powerful tools to gather genetic data has led geneticists to overlook the importance of analyzing that data as closely as possible. To read more about Moore's research, read the article "Moore and More" from the Spring 2010 issue of Dartmouth Medicine, or follow the links below to see how Moore is using a blog and Twitter to spread the word about his research. Also below are links to a few of the many papers Moore has written about epistasis.
Journal articles on Moore's research
- Bioinformatics challenges for genome-wide association studies
- Role for protein-protein interaction databases in human genetics
- Enabling personal genomics with an explicit test of epistasis
- Genetic population structure analysis in New Hampshire reveals Eastern European ancestry
- Epistasis and its implications for personal genetics
- From genotypes to genometypes: putting the genome back in genome-wide association studies
- Bladder cancer SNP panel predicts susceptibility and survival
- Shadows of complexity: what biological networks reveal about epistasis and pleiotropy
- Analysis of gene-gene interactions
- Concordance of multiple analytical approaches demonstrates a complex relationship between DNA repair gene SNPs, smoking and bladder cancer susceptibility
- A global view of epistasis
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