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An interview with José Conejo-Garcia - Glossary

Antigen-presenting cells
Cells that present antigens to T cells, providing the first signal in the process of T cell activation.

The death of a cell through genetic expression. This process often results in the death of unwanted or damaged cells.

The activation of the immune system in response to antigens produced by the host. Common autoimmune diseases include rheumatoid arthritis and multiple sclerosis.

A molecule that can interact with PILAR and is expressed on T cells

Costimulatory molecules
Molecules that provide the second signal in the process of T cell activation. These molecules are typically found on antigen-presenting cells. PILAR can also act as a costimulatory molecule, despite being expressed on T cells.

Proteins secreted by cells as part of an immune response.

Dendritic cells
A common antigen-presenting cell.

Blood cells involved in the immune response and often found in sites of inflammation.

Myeloid cells
Bone-marrow cells.

T cells
Lymphocytes involved in the adaptive immune response. Their roles in the immune system include attacking pathogens and recruiting other cells to join an immune response.

Th17 cells
A type of T cell that secretes the cytokine interleukin-17. Th17 cells are involved in protecting the body against some bacteria, but they are also involved in autoimmune responses.

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