Dartmouth Medicine HomeCurrent IssueAbout UsContact UsSearchPodcasts

Quicktime Required
Windows Media Required

Web Extras

Triterpenoids and Chemoprevention: A Dartmouth Collaboration

For 11 years, Dartmouth chemists Gordon Gribble and Tadashi Honda have collaborated with Dr. Michael Sporn, a professor of pharmacology and toxicology at Dartmouth Medical School, to create drugs that prevent and treat cancer. In 1998, Gribble's lab synthesized CDDO, a synthetic triterpenoid. This compound and one of its derivatives are now in clinical trials for a variety of cancers. So far, the drugs have proven to be quite safe and effective. For more on those trials and Sporn's research, read "Chemopreventatives show promise in trials". For a more in-depth look at this work, read the Winter 2006 feature "Compound Interest".


A Q&A with Gordon Gribble

Gordon Gribble Tells the Story of the Triterpenoid Project

See all for this issue

If you'd like to offer feedback about this article, we'd welcome getting your comments at DartMed@Dartmouth.edu.

This article may not be reproduced or reposted without permission. To inquire about permission, contact DartMed@Dartmouth.edu.

Dartmouth Medical SchoolDartmouth-Hitchcock Medical CenterWhite River Junction VAMCNorris Cotton Cancer CenterDartmouth College